| A new way to prepare core-shell biocompatible polymeric nano-particles from gelatin and acrylic acid |
| 關(guān)鍵詞： |
nano-particles interpolymer complex |
| 類 別： |
新產(chǎn)業(yè) >> 醫(yī)用材料 |
| 來 源： |
2005年新型纖維與聚合物材料國際學(xué)術(shù)會議（2005.10.19-21 上海） |
| 資料類型： |
pdf文件 |
| 資料大小： |
306K |
| 簡 介： |
Core-shell biocompatible polymeric nano-particles were obtained in aqueous solution with insoluble interpolymer complex of gelatin and poly (acrylic acid)(PAA) as core and soluble gelatin as shell (denoted as gelatin/PAA nano-particles). We prepared narrowly distributed gelatin/PAA nano-particles at relatively higher concentration (30mg/mL) via in-situ polymerization of acrylic acid in the aqueous solution of biocompatible gelatin. Dynamic light scattering and electrophoretic light scattering techniques were used to trace the in-situ polymerization process. Glutaraldehyde was used as cross-linking reagent for gelatin to lock the structure of the particles. Furthermore, the pH responsive behaviors of gelatin/PAA nano-particles before and after cross-linking were studied. |
| 上傳人： |
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| 上傳時間： |
2007-07-31 16:04:02 |
| 下載次數(shù)： |
28 |
| 消耗積分： |
2 |
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