63. Preparation and Drug Release Properties of CO2 Stimulus-sensitive Poly (N, N-dimethylaminoethyl methacrylate)-b-polystyrene Nanoparticles
作者：Xiaohong Wang, Guohua Jiang*, Zhen Wei, Xia Li, Bolin Tang
關(guān)鍵字：miniemulsion RAFT polymerization; CO?2 stimulus-sensitive; nanoparticles; drug release.
論文來源：期刊
具體來源：European Polymer Journal
發(fā)表時(shí)間：2013年
The CO2 stimulus-sensitive nanoparticles based on poly (N, N-dimethylaminoethyl methacrylate)-b-poly styrene (PDMAEMA-b-PS) were prepared via surfactant-free miniemulsion reversible addition-fragmentation chain transfer (RAFT) polymerization. The as-prepared nanoaprticles exhibited core-shell structure with about 120 nm in diameter. Their dispersion/aggregation in water can be adjusted by alternatively bubbling of CO2 and N2. Drug release from these nanoparticles can be accelerated (or delayed) by bubbling (or removing) of CO2.