Investigation of supramolecular synthons of p-hydroxybenzoic acid (PHBA): Comparison of its hydrate, co-crystal and salt
作者：Yang-Hui Luo, Bing Xu, Bai-Wang Sun*
關(guān)鍵字：Crystal Structure, Characterization, Organic Compounds, Salts
論文來源：期刊
具體來源：Journal of Crystal Growth
發(fā)表時(shí)間：2013年
An investigation of supramolecular synthons of p-hydroxybenzoic acid (PHBA) has been carried out in this work. Three different kinds of compounds derived fromPHBA (hydrate (1), co-crystal (2) and salt (3)) have been synthesized and characterized by single-crystal X-ray diffraction, infrared spectroscopy, differential scanning calorimetry (DSC) and thermogravimetric analyses (TGA). A thorough structural investigation revealed the different supramolecular synthons patterns of the three compounds: hydrate (1)—displays 1-D supramolecular sheet completed by water molecules; cocrystal (2)—displays square grid structure completed by hetero-dimeric unit; and salt(3)—forms hetero-dimeric unit and displays in?nite zigzag striped structure. We further prepared Hirshfeld surfaces for compounds 1–3 as well as PHBA, accompanied by vibrational spectroscopy, for the in-depth studies of intermolecular interactions in their solid-state forms.