Spontaneous Fusion between the Vesicles Formed by A(2n)(B-2)(n) Type Comb-Like Block Copolymers with a Semiflexible Hydrophobic Backbone
作者：Ying-Tao Liu, Ying Zhao, Hong Liu, Yu-Hua Liu, and Zhong-Yuan Lu*
關(guān)鍵字：Vesicles
論文來源：期刊
具體來源：Journal of Physical Chemistry B Volume: 113 Issue: 46 Pages: 15256-15262 Published: 2009
發(fā)表時間：2009年
The spontaneous vesicle formation and fusion of A2n(B2)n (n = 2?10) type comb-like block copolymers with semiflexible hydrophobic backbone are studied via dissipative particle dynamics (DPD) simulations. By systemically varying the solvent condition, we construct a phase diagram to indicate the thermodynamically stable region for vesicles. The spontaneous fusion between the vesicles is studied, whose mechanism is as follows: first, a stalk is formed between the vesicles; then, the holes appear in both vesicles near the feet of the stalk; finally, the stalk bends to circle the holes and the fusion process is completed. This fusion pathway is similar to that observed in Monte Carlo simulations and dynamic self-consistent filed theory but different from those reported in coarse-grained molecular dynamics and DPD simulations. The main reason for the difference may be attributed to the molecular structures used in different simulation techniques.