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High-efficiency loading in small mesopores (2–3 nm) forming a matrix type controlled drug delivery nanosystem
作者:Fang Liu, Hongwu Zhang,Qingyun Cao,Wuyi Zhou*, etal.
關(guān)鍵字:Mesoprous silica; Controlled drug delivery nanosystem; High-efficiency loading
論文來源:期刊
具體來源:RSC advances, 2014, 4, 8918-8921
發(fā)表時間:2014年
Herein a high-efficiency controlled release nanosystem for fluoroquinolonehydrochlorides was established by a characteristicvacuum-recrystal loaded process based on small pore mesoporousMCM-41. The system exhibited great drug loading capacity (62.31%),matrix type sustained-release behavior (5 days) and excellent biocompatibility in vitro.