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Crosslinking of poly(L-lactide) nanofibers with triallyl isocyanutrate by gamma-irradiation  
Crosslinking of poly(L-lactide) nanofibers with triallyl isocyanutrate by gamma-irradiation
資料類型: PDF文件
關(guān)鍵詞: poly  (L-lactide)  nanofibers  crosslinking  triallyl  isocyanutrate  gamma-irradiation  
資料大?。?/td> 2806K
所屬學(xué)科: 分子表征
來源: ICAFPM 2011先進纖維與聚合物材料國際學(xué)術(shù)會議(2011.8.15~17,上海)
簡介:
Poly(L-lactide)(PLLA)nanofiberhasattractedconsiderableattentionsduetoitspotentialapplicationasatissueengineeringscaffold,butitspoorthermalstabilityandmechanicalpropertiesrestrictitsapplications.Inthiswork,triallyisocyanurate(TAIC)wasaddedintoPLLAsolutionatdifferentratiosandfabricatedintonanofibrousmatsbyelectrospinningtechnique,thematswerethenirradiatedbygammarayatdifferentradiationdosestocrosslinkthePLLAchains.ThethermalpropertiesandbiodegradationpropertiesofdifferentPLLAsampleswereinvestigatedandcompared.Furthermore,theinvitrobiocompatibilitieswerealsoevaluatedbyusingmouseL929fibroblasts.Theresultsindicatedthatthethermalstabilityandtensilemechanicalpropertieswereincreasedaftercrosslinking,andthecrosslinkedsamplesirradiatedat10kGyexhibitedthebestenzymaticdegradation.TheinvitroresultsalsorevealedthatthecrosslinkedPLLA/TAICcompositenanofibersdidnotinducecytotoxiceffectsandsuitableforcellgrowth.Therefore,thecrosslinkedPLLAnanofibersareoneofthepromisingmaterialsforfuturetissueengineeringapplications.
作者: HE Chuanglong, FENG Wei, CAO Lijun, FAN Lingpeng
上傳時間: 2011-09-28 14:04:55
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