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Processing and Characterization of Supercritical C02 Batch Foamed Poly(lactic acid) Based Scaffolds for Tissue Engineering Application  
Processing and Characterization of Supercritical C02 Batch Foamed Poly(lactic acid) Based Scaffolds for Tissue Engineering Application
資料類型: PDF文件
關(guān)鍵詞: Poly(lactic  acid)  (PLA)  Poly  (  ethylene  glycol)  
(PEG)  Foams  Biodegradable  Tissue  engineering  
資料大?。?/td> 71K
所屬學科: 分子表征
來源: 第六屆亞歐研討會上處理和性能增強聚合物會議文集(2013.6.2-6 武漢)
簡介:
Bothpoly(lacticacid)(PLA)andpoly(ethyleneglycol)(PEG)arebiodegradablepolymers,andblendingPLAwithPEGisexpectedtotoughenPLAmatrixwhilemaintainitsbiodegradability.Inthisstudy,PLA/PEGblendsindifferentratioswerepreparedthroughtriple-screwextruder,andthefoamingbehaviorwasinvestigatedusingsupercriticalcarbondioxideasphysicalblowingagent.Themechanical,thermal,theologicalpropertiesandcrystallizationbehaviorwerealsostudied.BytheincorporationofPEG,theimpactstrengthofthePLA/PEGblendswasimprovedby98%,andthefailuremodetransferredfrombrittlefractureofneatPLAtoductilefractureofthePLA/PEGblendsasdemonstratedbythetensiletestandSEMmicrographs.TheviscoelasticityofthePLA/PEGmatrixwasweakened,andthecellstendedtobreakatthecellwallduringcellexpansion,thusahighlyinterconnectedstructurewithamaximumporosityof82.3%wasobtained.Moreover,thePLA/PEGblendsexhibitedhighercelldensitiesandsmallercellsizecomparedwiththeirneatcounterpart.
作者: B. Y. Chen, W. H. Zhang, H. B. Zhao, P. Yu, D. J. Fu, X. F. Peng
上傳時間: 2013-07-02 16:10:18
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